Left Atrium Involvement in Lymphoma Patients: Single Center Observational Study

Aim . To assess the structure and performance of left atrium (LA) before after 3 cycles anticancer treatment in lymphoma patients, as well incidences supraventricular arrhythmia (SVA) levels biomarkers inflammation. Material Methods This is a prospective observational study patients with confirmed diagnosis [n=23; 57% men; median age 52 (34;64) years], who had no prior polychemotherapy. The comparison group included persons without [n=18; 50% 43 (37; 54) years] comparable main terms sex, risk factors for cardiovascular diseases. Patients underwent 24h-ECG monitoring advanced transthoracic echocardiography at baseline (within months) treatment. Biomarkers inflammation were measured. results compared data group. Results In LA reservoir, conduit, booster function found to be impaired but these matched controls. After treatment, trend reduction conduit strain was found. proportion those SVA significantly higher chemotherapy anti-cancer or controls: vs 10% 33% respectively (p<0.05). Lymphoma number premature ventricular beats than control [183 (14;841) 38 (14;94) 9 (4;38) respectively]. There associations between parameters SVA. Moderate positive correlation ESR complexes (r S =0.44; p<0.05). A contractile inflammatory revealed: active ejection fraction (LA EF act ) =0.42, p<0.05); volume index β-globulin =0.43, neuregulin-1β expansion =0.55, Conclusions phasic regardless